Publications:
Semmes J, Feng Z, Adam BL, Banez LL, Bigbee WL, Campos D, Cazares L, Chan DW, Grizzle WE, Izbicka E, Kagan J, Malik G, McLerran D, Moul JW, Partin A, Prasanna P, Rozenzweig J, Sokoll LJ, Srivastava S, Srivastava S, Thompson IM, Welsh MJ, White N, Wignet M, Yasui Y, Zhang Z, Zou L (2005) Evaluation Of Serum Profiling By Surface-Enhanced Laser Desorption/ Ionization Time-Of-Flight Mass Spectrometry For The Detection Of Prostate Cancer: I. Assessment Of Platform Reproducibility. Clin Chem 51(1):102-112 Fowler LJ, Lovell MO, Izbicka E (2004) Fine-needle Aspiration in Preservcyt?: A Novel and Reproducible Method for Ancillary Proteomic Evaluation of Breast Neoplasms by SELDI-TOF. Mod Pathol17(8):1012-20 Grizzle WE, Semmes OJ, Basler J, Izbicka E, Feng Z, Kagan J, Adam BL, Troyer D, Srivastava S, Thornquist MD, Zhang Z, Thompson IM (2004) The Early Detection Research Network Surface-Enhanced Laser Desorption And Ionization Prostate Cancer Detection Study. A Study In Biomarker Validation In Genitourinary Oncology. Urologic Oncology 22(4):337-343 Nishioka D, Marcell V, Von Hoff DD, Izbicka E (2003) The use of early sea urchin embryos in anticancer drug testing. Methods in Molecular Biology/Medicine 85: 265-276 Izbicki T, Mazur J, Izbicka E (2003) Epidemiology And Etiology of Neuroblastoma: an Overview. Anticancer Res 23: 755-760 Izbicki T, Mazur J, Izbicka E (2003) Epidemiology Of Neuroblastoma: Analysis Of A Single Institution. Anticancer Res 23: 1933-1938 Izbicki T, Mazur J, Izbicka E (2003) Varicella zoster virus infections in neuroblastoma Patients: A 31-Year Clinical Study. Anticancer Res 23:3061-306 Kim MY, Gleason-Guzman M, Izbicka E, Nishioka D, Hurley LH (2003) The Selectivity of the Biological Effects of Telomestatin and TMPyP4 Can Be Attributed to Their Preference for Interaction with Intramolecular versus Intermolecular G-Quadruplex Structures. Cancer Res 63:3247-3265 Patnaik A, Eckhardt GA, Izbicka E, Tolcher AA, Hammond LA, Takimoto C, Schwartz G, McCreery H, Goetz A, Mori M, Terada K, Gentner L, Rybak ME, Richards H, Zhang S, Rowinsky EK (2003) A phase I, pharmacokinetic, and biological study of the farnesyltransferase inhibitor R115777 in combination with gemcitabine in patients with advanced malignancies. Clin Cancer Res 9:4761-4771
Proteomic analysis of formalin fixed paraffin embedded tissues using an improved method of extraction and digestion, R. Streeper, E. Izbicka, manuscript in preparation.
Evaluation of the effects of a-difluoromethylornithine (DFMO) on markers of cellular activity in a breast cancer chemoprevention study, E. Izbicka, R.T. Streeper, I.T. Yeh, O. Pressley, M. Grant, V. Andrews, J. Kuhn, J. O’Shaughnessy, submitted.
Izbicka E, Campos D, Carrizales G, Tolcher A (2005) Biomarkers For Sensitivity To Docetaxel And Paclitaxel In Human Tumor Cell Lines In Vitro. Cancer Genomics Proteomics 2:219-226
Izbicka E, Carrizales G, Campos D, Patnaik A (2005) Biomarkers Of Anticancer Activity Of R115777 (Tipifarnib, Zarnestra) In Combination With Paclitaxel In Human Breast Cancer Cells In Vitro. Anticancer Res 25(5):3215-3223
Izbicka E, Izbicki T (2005) Therapeutic Strategies For Treatment Of Neuroblastoma. Curr Opin Inv Drugs 12(6), 1200-1213
Medina-Gundrum L, Cerna C, Gomez L, Izbicka E (2005) Investigation Of HMN-176 Anticancer Activity In Human Tumor Specimens In Vitro And The Effects Of HMN-176 On Different Gene Expression. Inv New Drugs 23(1):3-9
Tolcher AW, Chi K, Kuhn J, Patnaik A, Takimoto C, Schwartz G, Thompson I, Berg K, D’Aloisio, Gleave M, Murray N, Frankel SR, Izbicka E, Rowinsky EK (2005) A Phase II, Pharmacokinetic, And Biologic Correlative Study Of Oblimersen Sodium (GenasenseTM, G3139), An Antisense Oligonucleotide Directed To The Bcl-2 m-RNA, With Docetaxel In Patients With Hormone-Refractory Prostate Cancer. Clin Cancer Res 11(10):3854-3861
Van Laar ES, Izbicka E, Medina-Gundrum L, MacDonald JR, Waters SJ (2004) Antitumor Activity Of Irofulven Against Human Ovarian Cancer Cell Lines, Human Tumor Colony-Forming Units, And Xenografts. Int J Gyn Cancer 14(5):824-831
Tolcher AW, Kuhn J, Schwartz G, Patnaik A, Hammond L, Thompson I, Fingert H, Bushnell D, Malik S, Kreisberg J, Izbicka E, Smetzer L, Rowinsky EK (2004) A Phase I, Pharmacokinetic, And Biologic Correlative Study Of Oblimersen Sodium (GenasenseTM, G3139), An Antisense Oligonucleotide Directed To The Bcl-2 m-RNA, With Docetaxel In Patients With Hormone-Refractory Prostate Cancer. Clin Cancer Res 10(15):5048-5057
Izbicka E, Tolcher AW (2004) Development of novel alkylating drugs as anticancer agents. Curr Opin Inv Drugs 5(6): 587-591
Grizzle WE, Adam BL, Bigbee WL, Conrads TP, Carroll C, Izbicka E, Jendoubi M, Johnsey D, Kagan J, Leach RJ, McCarthy DB, Semmes J, Srivastava S, Srivastava S, Thompson IM, Thornquist MD, Verma M, Zhang Z, Zou Z. (2004) Serum Protein Expression Profiling For Cancer Detection: Validation Of A SELDI-Based Approach For Prostate Cancer. Disease Markers 19 (3/4):185-195
Petit T, Davidson K, Cerna C, Lawrence R, Von Hoff DD, Izbicka E (2002) Investigation of the effects of ONYX adenovirus (ONYX-015) in combination with chemotherapeutic agents against human tumor cells in vitro. Anticancer Drugs 13: 47-50
Petit T, Davidson K, Cerna C, Lawrence R, Von Hoff DD, Izbicka E (2002) Investigation of the effects of ONYX adenovirus (ONYX-015) in combination with chemotherapeutic agents against human tumor cells in vitro. Anticancer Drugs 13: 47-50
Regulation of tumor signaling pathways by AZD3409 in vitro, R. Streeper, D. Campos, G. Carrizales, T.C. Stephens, E. Izbicka, Anticancer Res. 26 (6B), 4185-4189.
An Anti-Inflammatory C-Glucosyl Chromone from Aloe Barbadensis, J.A. Hutter, M. Salman, W.B. Stavinoha, N. Stasnagi, R.F. Williams, R.T. Streeper, S.T. Weintraub, Journal of Natural Products, 59(5), 541-543.
In vitro Metabolic Transformations of 2,4-Dipyrrolidinylpyrimidine, R.T. Streeper, Z.Zhao, P.G. Pearson, J.J. Vrbanac, Xenobiotica, 27(11), 1131-1135.
Molecular Pharmacology of Hepsulfam: Identification of Alkylated Nucleosides and Nucleobases, R.T. Streeper, M.E. Colvin. J. Hilton, R.J. Cotter, O.M. Colvin, Cancer Research, 55, 1491-1498, 1995.
Kinetic Analysis of the Reaction of Melphelan with Water, Phosphate and Glutathione, M.G. Bolton, J. Hilton, K.D. Robertson, R.T. Streeper, O.M. Colvin, D.A. Noe, Drug Metabolism and Disposition, 21(6), 986-996, 1993.
Hepsulfan Sensitivity in Human Breast Cancer Cell Lines: The Role of Glutathione and Glutathione S-Transferase in Resistance, D.K. Armstrong, G.B. Gordon, J. Hilton, R.T. Streeper, O.M. Colvin, N.E. Davidson, Cancer Research, 52, 1416-1421, 1992.
Presentations:
Izbicka E, Streeper R, West F, Yeh I (2007) Differential Proteomic Profiles Observed In FFPE Breast Tissue Specimens Of Several Pathologic States. Proc 30th San Antonio Breast Cancer Symposium
Izbicka E, Campos D, Baek S, Streeper R, Diaz A, Thompson I (2007) Novel serum biomarkers for renal cell carcinoma. Proc AACR 48:534
Campos D, Streeper R, Diaz A, Wick M, Takimoto C, Sidransky D, Demetri G, Rowinsky E, Poradosu E, Izbicka E (2006). Towards personalized medicine: evaluation of blood and tissue biomarkers for drug sensitivity in human xenograft models in vivo. Molecular Diagnostics in Cancer Therapeutic Development: Maximizing Opportunities for Individualized Treatment. Chicago, Illinois
Streeper R, Campos D, Izbicka E (2006) Improved method for preparation of formalin-fixed paraffin-embedded tissue for mass spectrometric analysis. Proc AACR/NCI/EORTC International Conference on Molecular Targets and Cancer Therapeutics, Prague, Czech Republic
Campos D, Streeper R, Cornell J, Izbicka E (2006) Rapid, efficient and reproducible SELDI chip robotic preparation method. Proc AACR/NCI/EORTC International Conference on Molecular Targets and Cancer Therapeutics, Prague, Czech Republic
Yeh I, Beeram S, Campos D, Streeper R, Villafan-Reed K, Izbicka E (2006) Differential Proteomic Analysis of Formalin Fixed Paraffin Embedded Breast Tissue Encompassing a Range of Pathologic States. Proc 29th San Antonio Breast Cancer Symposium
Structural Elucidation of C-Glucosyl Chromones for Aloe Barbadensis, J.A. Miller, S.T. Weintraub, R.T. Streeper, W.B. Stavinoha, 44th ASMS Conference on Mass Spectrometry and Allied Topics, May 13-17, 1996, Portland, Oregon.
Characterizaiton of Acidic Triterpenes by HPLC-ESIMS, S.T. Weintraub, R.T. Streeper, N. Stasnagi, W,B. Stavinoha, 43rd ASMS conference on Mass Spectrometry and Allied Topics, May 21-26, 1995, Atlanta, Georgia.